Moreover, free amino acid can endanger long‐term storage as traces of the complimentary amine advertise autocatalytic Fmoc cleavage. Suppliers provide either a GC‐based approach with a restriction of detection of 0.2% or a semiquantitative TLC‐ninhydrin assay. The International Conference on Harmonisation for standards of active pharmaceutical ingredient manufacturing (Q11) requires optical pureness, Suggested Internet page …